Outlook .OST file issue

I'm using Outlook 2016 in Windows 10 and every time I close at the end of the day, when I restart the next day my Outlook starts but then gives an error that it can't start and then closes. I have deleted my .OST file and then restarted Outlook where everything works fine until I close Outlook. The process repeats itself every time. This started after the last major Microsoft updates. I also tried creating a new profile with the same result.