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test POP3 error: 550 5.7.1 client unable to relay

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My outlook connect exchange 2013 server via POP3,  it is connecting popup error message: 550 5.7.1 unable to relay. Some users can connect exchange 2013 server via pop3, but some users cannot connect. I same also checked the permission of exchange server receive connector , It should be is good. I also checked the permission of AD user, Please view the following:

NT AUTHORITY\SELF             False                         {GenericRead}                                             
NT AUTHORITY\SELF             False                         {ExtendedRight}               {Send-As}                   
NT AUTHORITY\SELF             False                         {ReadProperty, WriteProperty}                             
NT AUTHORITY\SELF             False                         {ExtendedRight}               {Receive-As}                
NT AUTHORITY\SELF             False                         {ExtendedRight}               {User-Change-Password}       
NT AUTHORITY\SELF             False                         {ReadProperty, WriteProperty}                             
NT AUTHORITY\SELF             False                         {ReadProperty, WriteProperty}                             
NT AUTHORITY\SELF             False                         {ReadProperty, WriteProper... {Private-Information} 

Excuse me, how to solve the problem, thank you !



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