I have a virtualised environment.
----The setup:-----
two vHosts, vmware 5.5, 4 CPU, 196 GB RAM, Storewize v3700, 20 10K disks in RAID10
two win 2012 exchange 2013 servers
two win2012 DCs
five (5) Win2008R2 RDS hosts + 1 2008R2 Connection broker
60 users on the RDS server in outlook online-mode. no cache
Office 2013 on the servers
-----the problem:---
Some random users have random problems opening outlook.
A user tries to open outlook and gets the message "exchange server not avaliable".. he says OK, and outlook closes. - opens outlook again, and everything works..
This happens at random times for random users
CPU, disk and network activity are very low on both vhosts and there is a lot of avaliable RAM on all guests
I don't know if its related, but the larger the mailbox is, the longer it takes to open outlook.. some times up to 6-10 seconds.. At idle times, outlook opens in less than a second..
Any ideas?