Your changes were not saved because of a Microsoft Exchange error OWA Exchange 2007 SP3

Hi,

I"m running Exchange 2007 SP3 on VM running Server 2008 Enterprise.

When I try and save my OOF, change Regional Settings or Appearance, I get a message saying "Your changes were not saved because of a Microsoft Exchange error"

I've checked the logs in Event Viewer which isn't showing any errors.

Suggestions welcomed.

Thanks in Advance,

Adam