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outlook issue connectiong using POP3/SMTP (login denied)

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HI,

we have issue connecting (outlook, Thunderbird) to exchange using SMTP outgoing setting

Our environment consist of (2 cas server behind loadbalancer, 2 DB with DAG enabled), exchange 2013

received connector configured as below:

--------------------------------------------------------------------

Identity         : SPT-EXC-MBX01\Client Proxy EXC-MBX01
Bindings         : {0.0.0.0:995, 0.0.0.0:993, 0.0.0.0:587, [::]:587}
AuthMechanism    : Tls, Integrated, BasicAuth, BasicAuthRequireTLS, ExchangeServer
PermissionGroups : AnonymousUsers, ExchangeUsers, ExchangeServers, Custom
RequireTLS       : False
EnableAuthGSSAPI : True

Identity         : SPT-EXC-MBX02\Client Proxy EXC-MBX02
Bindings         : {0.0.0.0:587, [::]:587}
AuthMechanism    : Tls, Integrated, BasicAuth, BasicAuthRequireTLS, ExchangeServer
PermissionGroups : AnonymousUsers, ExchangeUsers, ExchangeServers, Custom
RequireTLS       : False
EnableAuthGSSAPI : True


Identity         : SPT-EXC-CAS03\Client Frontend EXC-CAS03
Bindings         : {[::]:587, 0.0.0.0:587}
AuthMechanism    : Tls, Integrated, BasicAuth, BasicAuthRequireTLS
PermissionGroups : AnonymousUsers, ExchangeUsers, Custom
RequireTLS       : False
EnableAuthGSSAPI : True

Identity         : SPT-EXC-CAS04\Client Frontend EXC-CAS04
Bindings         : {[::]:587, 0.0.0.0:587}
AuthMechanism    : Tls, Integrated, BasicAuth, BasicAuthRequireTLS
PermissionGroups : AnonymousUsers, ExchangeUsers, Custom
RequireTLS       : False
EnableAuthGSSAPI : True

----------------------------------------------------------------------------

outlook configured to use smtp outgiong port 587 using TLS,

thunderbird detect it to use 587 and Kerbers/GSSAPI ( but can't send email also)

receive connector on both server show the below error:

-----------------------------

EXC-CAS03\Client Frontend EXC-CAS03,08D6AED1441FE0A0,30,10.10.210.107:587,10.10.210.13:38544,*,,Setting up client proxy session failed with error: 421 4.2.1 Unable to connect
EXC-CAS03\Client Frontend EXC-CAS03,08D6AED1441FE0A0,32,10.10.210.107:587,10.10.210.13:38544,*,,"Setting up client proxy session failed with error: 441 4.4.1 Error encountered while communicating with primary target IP address: ""Failed to connect. Winsock error code: 10061, Win32 error code: 10061."" Attempted failover to alternate host, but that did not succeed. Either there are no alternate hosts, or delivery failed to all alternate hosts. The last endpoint attempted was 10.10.210.103:465"
EXC-CAS03\Client Frontend EXC-CAS03,08D6AED1441FE0A0,34,10.10.210.107:587,10.10.210.13:38544,>,451 4.7.0 Temporary server error. Please try again later. PRX5 ,

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and sometimes
EXC-CAS03\Client Frontend EXC-CAS03,08D6AED1441FE0A0,35,10.10.210.107:587,10.10.210.13:38544,-,,Remote(SocketError)

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any help here please.


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